Posts Categorized: News

CRISPR 2016 In Review

CRIPSR was first remarked on in 1987 by Yoshiizumi Ishino, Osaka University.  It wasn’t until 2002, fifteen years later that it’s name was coined, Clustered Regularly Interspaced Short Palindromic Repeats.  Ten years after that in 2012, Doudna and Charpentier changed the game by tweaking CRISPR, using it to edit and engineer genomes.  In the subsequent… Tags: , , , , , , ,

Categories: News

RED LIGHT STOP, GREEN LIGHT GO – KINASE ACTIVATION NOW HAS ON/OFF SWITCH

Kinases are vital proteins that can affect reaction stability, signal transmission, and protein activity and regulation.  Basically they are involved in nearly all cellular pathways.  There are numerous types of kinases existing throughout the body.  When not functioning properly they can lead to cancer and other diseases.  It has been long understood how to turn… Tags: , , , , , , ,

Categories: News

3 Interview Questions and How To Nail Them

Not all interview questions are straight and to the point. Some may have you sitting there scratching your head. The last thing you want to do is appear unprepared in front of the hiring managers. Here are 3 questions that can seem intimidating but with some practice you can nail them. Why should we hire…

Categories: News

Chemo Response Foretold by Leukemia Stem Cell Biomarker

Princess Margaret Cancer Centre in Toronto is utilizing LSC17, a biomarker found in Leukemia Stem Cells, to determine if conventional treatments will be effective.  If present, the biomarker causes greater chance of relapse.  LSC17 causes makes cells dormant, allowing them to avoid effects of chemotherapy, developing after presumed remission.   Here Are The Details: Stem… Tags: , , , , , , , ,

Categories: News

Molecular Switch Finding May Help Drive Stem Cells to Desired Cell Type

Using CRISPR, epigenetic researchers at the Babraham Institute in the United Kingdom control gene activity in human embryonic stem cells.  The understanding of the targeted molecular switches on PRC2 increases the efficiency of differentiating stem cells, furthering their regenerative medicine research. Here are their findings: During development of an embryo and during the specialization of… Tags: , , , , , ,

Categories: News

Novel Technique May Lead to Design of New and Improved Antibiotics

Scientists at the University of North Carolina say they have discovered a way to make precise changes to an enzyme-driven “assembly line” allowing researchers to improve or change the properties of an existing antibiotic. Their findings being the first to successfully and efficiently manipulate which building blocks the enzyme selects in the act of synthesizing… Tags: , , ,

Categories: News

Italian Pharma, Chiesi Buys Asthma Company Putting It Against Novartis

A privately owned Italian pharmacy called Chiesi Farmaceutici bought all outstanding shares and assets from the asthma-focused biotech, Atopix Therapeutics. This deal puts Chiesi against an established eosinophilic asthma market. A market which includes targeted biologics such as GlaxoSmithKline’s Nucala and Teva’s Cinqair/Cinqaero, both who are approved worldwide. Here are the details: Buying all outstanding… Tags: , , , , ,

Categories: News

How Loneliness is Linked to Alzheimer’s Disease

More evidence is surfacing that shows a link between loneliness and cognitive decline that could lead to Alzheimer’s disease.  It isn’t exactly social isolation that is connected to cognitive decline, but rather the actual emotion of feeling lonely. In other words, if an adult feels left out, even though they are surrounded by other people, they… Tags: , , , , , , ,

Categories: News

Plasmids Shown to Play Key Role in Spread of Antibiotic Resistance

Antibiotic resistance represents a significant public health problem. A report from the O’Neill Commission predicts that antibiotic resistance will lead to 10 million deaths per year by 2050, surpassing cancer as a source of human mortality. According to Researchers at the University of Oxford, plasmids are one of the key culprits in spreading the major global… Tags: , , , , , , , , , ,

Categories: News

Oncolytic Viruses – Going to New Lengths

Virus are a staple in science for recombining DNA and can be used to develop viral vaccines or as vectors in gene therapy.  With the progress made in next generation sequencing, designing nucleic acid constructs and genomes can happen in hours and days rather than weeks and months.  Leading scientist, Bruce Smith, V.M.D., Ph.D. at… Read more »