Senior Medical Director-Neurodegeneration

Lead the clinical strategy shaping the future of RNA‑based therapies for neurodegenerative disease.

R&D Partners is seeking a Senior Medical Director with deep expertise in neurodegenerative diseases to provide clinical leadership across an expanding pipeline of RNA‑based therapeutics. This role offers the opportunity to lead clinical development programs with a primary focus on Huntington’s Disease, while also supporting additional therapeutic areas as the portfolio evolves.

The position requires strategic oversight of clinical trials, close collaboration with cross‑functional teams, and meaningful engagement with external experts and regulatory authorities.

Please note that to be considered for this role you must have the right to work in this location.

Key Responsibilities

• Serve as the clinical and strategic leader for assigned development programs, driving progress, quality, and operational excellence
• Develop innovative yet practical clinical development strategies and support global regulatory approval pathways
• Oversee clinical trial conduct and safety, ensuring adherence to timelines, quality standards, and deliverables
• Provide strategic clinical input to research teams on development feasibility, target validation, and proof‑of‑concept study design
• Collaborate closely with Preclinical, Regulatory Affairs, Biostatistics, Clinical Operations, Medical Affairs, Commercial, and Quality teams to ensure integrated development strategies
• Lead and supervise major clinical deliverables, including regulatory submissions, manuscripts, abstracts, and presentations
• Review and approve controlled documents such as clinical protocols, Investigator’s Brochures, and informed consent forms, in line with SOPs
• Represent clinical programs in external forums, including regulatory interactions, advisory boards, and scientific conferences

Key Skills and Requirements:

• Education: MD or MD/PhD with a strong research background; Board Certification or specialist training preferred.

Experience:

• 10+ years of industry experience, ideally in neurology and Huntington’s Disease drug development.
• Proven track record of leading Phase II-III clinical programs and engaging with Health Authorities.

Skills:

• Sound scientific and clinical judgment.
• Expertise in clinical research, trial design, biostatistics, and regulatory guidelines.
• Exceptional communication skills for presenting complex medical concepts.
• Leadership and collaboration within a matrix environment.
• Familiarity with biotech-pharma partnerships is a plus.

Attributes:

• Problem-solving ability with balanced judgment.
• Entrepreneurial mindset aligned with a culture of science, passion, and urgency.

For more information, please contact Calum Watson.

If you are interested in applying to this exciting opportunity, then please click ‘Apply’ or to speak to one of our specialists visit the ‘Contact Us’ page.

R&D Partners is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. R&D Partners is acting as an Employment Agency in relation to this vacancy.

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