Principal Scientist

Drive innovation in bioanalysis as a Principal Scientist shaping the future of regulated LC-MS pipelines.

R&D Partners is seeking a Principal Scientist – Bioanalytical (LCMS) to join a leading CRO and laboratory services organization in South Wales. This is a senior technical role for a subject matter expert in bioanalytical sciences, focusing on analytical method development, validation, and study delivery using ELISA and/or LC-MS/MS methodologies within a regulated environment. The successful candidate will play a pivotal role in scientific leadership, client engagement, and the ongoing development of laboratory capabilities.

Please note that to be considered for this role you must have the right to work in this location.

Responsibilities:

• Lead the development, validation, transfer, and optimization of ELISA and/or LC-MS/MS analytical methods.
• Provide scientific oversight of bioanalytical studies, ensuring delivery meets quality, regulatory, and timeline expectations.
• Review, interpret, and approve analytical data, study reports, protocols, and technical documentation.
• Act as a technical expert to troubleshoot complex analytical and assay-related challenges.
• Ensure compliance with GxP regulations, data integrity standards, and laboratory quality requirements.
• Mentor and support the development of scientific staff, providing technical guidance across the laboratory.
• Contribute to client interactions, technical discussions, audits, and business development activities as a senior representative of the function.

Key Skills and Requirements:

• Degree in a relevant scientific discipline (MSc or PhD advantageous).
• Extensive experience with ELISA and/or LC-MS/MS techniques in a regulated laboratory environment.
• Proven expertise in bioanalytical method development, validation, transfer, and routine sample analysis.
• Strong understanding of GxP requirements, bioanalytical method validation, and data integrity principles.
• Demonstrable experience reviewing analytical data and producing regulatory-standard documentation.
• Ability to manage multiple projects, priorities, and stakeholders while delivering high-quality outcomes.
• Excellent communication skills with experience engaging clients, auditors, and cross-functional teams.

Desirable Experience:

• CRO, clinical research, or clinical trials experience.
• Practical expertise across both ELISA and LC-MS/MS platforms.
• Experience supporting regulatory inspections and client audits.
• Knowledge of laboratory process improvement and operational excellence initiatives.
• Previous mentoring, leadership, or line management experience.

What’s on Offer:

• Opportunity to join a growing and highly respected scientific organization.
• Exposure to cutting-edge bioanalytical studies supporting drug development.
• Significant technical influence and leadership responsibility.
• Collaborative and scientifically driven working environment.
• Long-term career development and progression opportunities.

Important Information:

• Candidates must have full right to work in the UK to be eligible for this role.
• Sponsorships are not available for this position.

For more information, please contact Timi Asseez.

If you are interested in applying to this exciting opportunity, then please click ‘Apply’ or to speak to one of our specialists visit the ‘Contact Us’ page.

R&D Partners is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. R&D Partners is acting as an Employment Agency in relation to this vacancy.

By submitting this application, you confirm that you’ve read and understood our privacy policy, which informs you how we process and safeguard your data – https://www.r-dpartners.com/privacy-policy/