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Senior Scientist, Oligonucleotide Design and Chemistry

Senior Scientist, Oligonucleotide Design and Chemistry

Reference: ROCGJP00040066
Date posted: 31/03/2026
Job details
Specialism
Scientific
Expertise
Purification
Location
South San Francisco, California, USA
Job type
Contract
Salary
£130,832.00 to £174,330.00
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Description

R&D Partners is seeking to hire a Senior Scientist, Oligonucleotide Design and Chemistry in South San Francisco, CA.

Your main responsibilities as a Senior Scientist, Oligonucleotide Design and Chemistry:

· Lead the design, synthesis, and characterization of novel oligonucleotides for various portfolio programs.

· Provide mentorship to junior scientists in the synthesis and characterization of new oligonucleotide sequences.

· Serve as a leader or active participant in cross-disciplinary discussions to ensure effective execution of portfolio programs.

· Collaborate with biology and biochemistry teams to design and execute novel assays, facilitating rapid go/no-go decisions.

· Take a leading role in managing all aspects of laboratory instrumentation and maintaining smooth operations.

What we are looking for in a Senior Scientist, Oligonucleotide Design and Chemistry:

· Must have attained a Masters Degree or higher.

· Required majors: Chemistry, biochemistry, chemical biology, or related fields.

· Extensive hands-on experience in the synthesis, purification, and analytics of siRNA and/or ASO therapeutics.

· In-depth knowledge of oligonucleotide/peptide therapeutics, including chemical structure search tools, synthesis techniques, purification instrumentation, and analysis methods for chemically modified oligonucleotides.

· Demonstrated ability to both lead and support multiple parallel projects and thrive in highly collaborative team environments.

Why Choose R&D Partners?

As an employee, you have access to a comprehensive benefits package including:

  • Medical insurance – PPO, HMO &
  • Dental & Vision insurance
  • 401k plan
  • Employee Assistance Program
  • Long-term disability
  • Weekly payroll
  • Expense reimbursement
  • Online timecard approval

Pay Scale:

$130,832 – $174,330 Dependent on Experience)

R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.

R&D Partners is an equal-opportunity employer.

If you are interested in applying to this exciting opportunity, then please click ‘Apply’ or to speak to one of our specialists visit the ‘Contact Us’ page.

R&D Partners is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. R&D Partners is acting as an Employment Agency in relation to this vacancy.

By submitting this application, you confirm that you’ve read and understood our privacy policy, which informs you how we process and safeguard your data – https://www.r-dpartners.com/privacy-policy/

Apply for this role
Register your interest

If you can’t find your ideal role with us right now, we’d still love to hear from you! Send us your CV and we’ll contact you if a suitable role becomes available.

Register interest

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